https://doi.org/10.4081/mem.2004.635
Preimplantation diagnosis.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Preimplantation diagnosis procedure appeared in the clinical practice together with the introduction of artificial fertilization techniques, as a way to improve the success of IVF and ICSI cycles by selecting the embryos of higher quality, which are more suitable for replacement into the uterus. Particularly, preimplantation genetic diagnosis was developed as an alternative to prenatal diagnosis to screen embryos for common or age-related aneuploidies for infertile couples, or to avoid the substantial risk of transmission of severe genetic diseases for fertile couples. Samples for preimplantation genetic diagnosis are obtained from oocytes or cleaving embryos after IVF or ICSI. Article reviews different techniques and clinical applications of the preimplantation diagnosis, it describes limits and risks of these procedures, and also represents the bioethical debate on this matter. Between the most important ethics concerns the problem of preimplantation diagnosis and embryo selection as alternative to abortion after post-implantation diagnosis, social sexing selection and for donors of stem cells selection appear. From the same bioethical debate the eugenic aim of preimplantation diagnosis emerges, a perverse aim because no individual human life can be evaluated, selected, left die or suppressed because of "its own quality".
How to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
An Open Access Publication is one that meets the following two conditions:
- the author(s) and copyright holder(s) grant(s) to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship, as well as the right to make small numbers of printed copies for their personal use.
- a complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable open access, unrestricted distribution, interoperability, and long-term archiving.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.